Shahid Beheshti University Journal of Neurodevelopmental Cognition 2645-565X 1 1 2022 03 03 Neuro-Cognitive Remediation of Emotion Processing in Patients with Borderline Personality Disorder through Psychotherapy 1 6 103421 10.52547/jncog.2022.103421 EN Elahe Majdara Faculty of Psychology and Educational Science, Semnan University, Semnan, Iran Isaac Rahimian Boogar Faculty of Psychology and Educational Science, Semnan University, Semnan, Iran Siavash Talepasand Faculty of Psychology and Educational Science, Semnan University, Semnan, Iran Robert J. Gregory Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, State University of New York, New York, United States of America Journal Article 2022 02 02 Dynamic Deconstructive Psychotherapy has used neuroscience findings to propose the specific neuroaffective deficits in the processing the emotion experiences as etiology of the borderline personality disorder. The purpose of this study was to evaluate the efficacy of Dynamic Deconstructive Psychotherapy to improve the symptoms in patients diagnosed with borderline personality disorder by remediation of neuro-affective defects. This study was designed as a randomized controlled trial using the pre-test, post-test and a control group. Thirty patients who were diagnosed with borderline personality disorder met the inclusion criteria, randomly divided into two groups. Both groups were evaluated using both Borderline Evaluation of Severity Over Time (BEST) and Patient Health Questionnaire Mood Scale (PHQ-9) questionnaires at the baseline and the over course of the treatment. Data analysis using repeated measures ANOVA indicated that the effect of measuring time (p=0.001) and time/group (p=0.010) on the linear combination of the severity of borderline disorder and depression was significant. This result supports the efficacy of Dynamic Deconstructive Psychotherapy based on the neurocognitive remediation of emotion processing using association, attribution, and alterity techniques. https://jncog.sbu.ac.ir/article_103421_c06d84bbc0dfaf84b37d97f8f88dd1fe.pdf